FANCI is a second monoubiquitinated member of the Fanconi anemia pathway (original) (raw)

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Acknowledgements

We thank the affected individuals and their families and the many physicians that have referred families to the International Fanconi Anemia Registry for participation in the research. We thank H. Joenje (VU University Medical Center) for providing the FA-I reference cell line EUFA592, K. Nakanishi, M. Jasin (Memorial Sloan-Kettering Cancer Center), T. Taniguchi (Fred Hutchinson Cancer Research Center) and A. D'Andrea (Dana-Farber Cancer Institute) for cell lines and reagents, Deutsche FA-Hilfe and R. Dietrich for research support, members of T.T.H.'s, D.Bar-Sagi and D. Reinberg laboratories (New York University) for technical assistance, equipment and helpful discussions, and H. Wang (SeqWright) for providing technical expertise. This work was supported in part by Deutsche Forschungsgemeinschaft grant Ha2322/2-1 and German Jose Carreras Leukemia Foundation R06/21 (H.H.), US National Institutes of Health grant R37HL32987 (A.D.A.) and New York University School of Medicine start-up funding (T.T.H.).

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Author notes

  1. Ashley E Sims and Elizabeth Spiteri: These authors contributed equally to this work.

Authors and Affiliations

  1. Department of Biochemistry, New York University School of Medicine, New York, 10016, New York, USA
    Ashley E Sims, Robert J Sims III, Adriana G Arita & Tony T Huang
  2. Laboratory of Human Genetics and Hematology, The Rockefeller University, New York, 10021, New York, USA
    Elizabeth Spiteri, Francis P Lach, Thomas Landers & Arleen D Auerbach
  3. Department of Pediatric Hematology, Oncology and Clinical Immunology, Children's Hospital, Heinrich Heine University, Duesseldorf, D-40225, Germany
    Melanie Wurm, Marcel Freund & Helmut Hanenberg
  4. Department of Human Genetics, University of Wuerzburg, Wuerzberg, D-97074, Germany
    Kornelia Neveling
  5. Department of Pediatrics, Wells Center for Pediatric Research, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, 46202, Indiana, USA
    Helmut Hanenberg

Authors

  1. Ashley E Sims
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  2. Elizabeth Spiteri
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  3. Robert J Sims III
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  4. Adriana G Arita
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  5. Francis P Lach
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  6. Thomas Landers
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  7. Melanie Wurm
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  8. Marcel Freund
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  9. Kornelia Neveling
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  10. Helmut Hanenberg
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  11. Arleen D Auerbach
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  12. Tony T Huang
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Corresponding author

Correspondence toTony T Huang.

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Sims, A., Spiteri, E., Sims, R. et al. FANCI is a second monoubiquitinated member of the Fanconi anemia pathway.Nat Struct Mol Biol 14, 564–567 (2007). https://doi.org/10.1038/nsmb1252

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