Mapping of interactions and mouse congenic strains identified novel epistatic QTLs controlling the persistence of Salmonella Enteritidis in mice (original) (raw)

• CDC. Center for Disease Control and Prevention Report. Division of bacterial and mycotic diseases. Disease information, www.cdc.gov, Atlanta, Giorgia, December 2003.
• Roy MF, Malo D . Genetic regulation of host responses to Salmonella infection in mice. Genes Immun 2002; 3: 381–393.
  Article CAS PubMed Google Scholar
• O'Brien AD, Scher I, Formal SB . Effect of silica on the innate resistance of inbred mice to Salmonella typhimurium infection. Infect Immun 1979; 25: 513–520.
  CAS PubMed PubMed Central Google Scholar
• Nauciel C, Vilde F, Ronco E . Host response to infection with a temperature-sensitive mutant of Salmonella typhimurium in a susceptible and a resistant strain of mice. Infect Immun 1985; 49: 523–527.
  CAS PubMed PubMed Central Google Scholar
• Barthel M, Hapfelmeier S, Quintanilla-Martinez L et al. Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host. Infect Immun 2003; 71: 2839–2858.
  Article CAS PubMed PubMed Central Google Scholar
• Young D, Hussell T, Dougan G . Chronic bacterial infections: living with unwanted guests. Nat Immunol 2002; 3: 1026–1032.
  Article CAS PubMed Google Scholar
• Monack DM, Bouley DM, Falkow S . Salmonella typhimurium persists within macrophage. J Exp Med 2004; 199: 231–241.
  Article CAS PubMed PubMed Central Google Scholar
• Caron J, Loredo-Osti JC, Laroche L, Skamene E, Morgan K, Malo D . Identification of genetic loci controlling bacterial clearance in experimental Salmonella enteritidis infection: an unexpected role of Nramp1 (Slc11a1) in the persistence of infection in mice. Genes Immun 2002; 3: 196–204.
  Article CAS PubMed Google Scholar
• Kim JH, Sen S, Avery CS et al. Genetic analysis of a new mouse model for non-insulin-dependent diabetes. Genomics 2001; 74: 273–286.
  Article CAS PubMed Google Scholar
• Xu J, Langefeld CD, Zheng SL et al. Interaction effect of PTEN and CDKN1B chromosomal regions on prostate cancer linkage. Hum Genet 2004; 115: 255–262.
  CAS PubMed Google Scholar
• Buer J, Balling R . Mice, microbes and models of infection. Nat Rev Genet 2003; 4: 195–205.
  Article CAS PubMed Google Scholar
• Casanova JL, Abel L . The human model: a genetic dissection of immunity to infection in natural conditions. Nat Rev Immunol 2004; 4: 55–66.
  Article CAS PubMed Google Scholar
• Sukupolvi S, Edelstein A, Rhen M, Normark SJ, Pfeifer JD . Development of a murine model of chronic Salmonella infection. Infect Immun 1997; 65: 838–842.
  CAS PubMed PubMed Central Google Scholar
• Malo D, Vogan K, Vidal S et al. Haplotype mapping and sequence analysis of the mouse Nramp gene predict susceptibility to infection with intracellular parasites. Genomics 1994; 23: 51–61.
  Article CAS PubMed Google Scholar
• Vidal S, Tremblay ML, Govoni G et al. The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. J Exp Med 1995; 182: 655–666.
  Article CAS PubMed Google Scholar
• Carlborg O, Haley CS . Epistasis: too often neglected in complex trait studies? Nat Rev Genet 2004; 5: 618–625.
  Article CAS PubMed Google Scholar
• Kao CH, Zeng ZB, Teasdale RD . Multiple interval mapping for quantitative trait loci. Genetics 1999; 152: 1203–1216.
  CAS PubMed PubMed Central Google Scholar
• Pociot F, Karlsen AE, Pedersen CB, Aalund M, Nerup J . Novel analytical methods applied to type 1 diabetes genome-scan data. Am J Hum Genet 2004; 74: 647–660.
  Article CAS PubMed PubMed Central Google Scholar
• Naumova AK, Leppert M, Barker DF, Morgan K, Sapienza C . Parental origin-dependent, male offspring-specific transmission-ratio distortion at loci on the human X chromosome. Am J Hum Genet 1998; 62: 1493–1499.
  Article CAS PubMed PubMed Central Google Scholar
• Naumova A, Sapienza C . The genetics of retinoblastoma, revisited. Am J Hum Genet 1994; 54: 264–273.
  Article CAS PubMed PubMed Central Google Scholar
• Naumova AK, Greenwood CM, Morgan K . Imprinting and deviation from Mendelian transmission ratios. Genome 2001; 44: 311–320.
  Article CAS PubMed Google Scholar
• Croteau S, Andrade MF, Huang F, Greenwood CM, Morgan K, Naumova AK . Inheritance patterns of maternal alleles in imprinted regions of the mouse genome at different stages of development. Mamm Genome 2002; 13: 24–29.
  Article CAS PubMed Google Scholar
• Cattanach BM, Beechey CV, Peters J . Interactions between imprinting effects in the mouse. Genetics 2004; 168: 397–413.
  Article CAS PubMed PubMed Central Google Scholar
• Vidal SM, Pinner E, Lepage P, Gauthier S, Gros P . Natural resistance to intracellular infections: Nramp1 encodes a membrane phosphoglycoprotein absent in macrophages from susceptible (Nramp1 D169) mouse strains. J Immunol 1996; 157: 3559–3568.
  CAS PubMed Google Scholar
• Gruenheid S, Finlay BB . Microbial pathogenesis and cytoskeletal function. Nature 2003; 422: 775–781.
  Article CAS PubMed Google Scholar
• Forbes JR, Gros P . Iron, manganese, and cobalt transport by Nramp1 (Slc11a1) and Nramp2 (Slc11a2) expressed at the plasma membrane. Blood 2003; 102: 1884–1892.
  Article CAS PubMed Google Scholar
• Gruenheid S, Pinner E, Desjardins M, Gros P . Natural resistance to infection with intracellular pathogens: the Nramp1 protein is recruited to the membrane of the phagosome. J Exp Med 1997; 185: 717–730.
  Article CAS PubMed PubMed Central Google Scholar
• Cuellar-Mata P, Jabado N, Liu J et al. Nramp1 modifies the fusion of Salmonella typhimurium-containing vacuoles with cellular endomembranes in macrophages. J Biol Chem 2002; 277: 2258–2265.
  Article CAS PubMed Google Scholar
• Jabado N, Cuellar-Mata P, Grinstein S, Gros P . Iron chelators modulate the fusogenic properties of _Salmonella_-containing phagosomes. Proc Natl Acad Sci USA 2003; 100: 6127–6132.
  Article CAS PubMed PubMed Central Google Scholar
• Singh PK, Parsek MR, Greenberg EP, Welsh MJ . A component of innate immunity prevents bacterial biofilm development. Nature 2002; 417: 552–555.
  Article CAS PubMed Google Scholar
• Nicolas G, Bennoun M, Devaux I et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA 2001; 98: 8780–8785.
  Article CAS PubMed PubMed Central Google Scholar
• Nicolas G, Viatte L, Bennoun M, Beaumont C, Kahn A, Vaulont S . Hepcidin, a new iron regulatory peptide. Blood Cells Mol Dis 2002; 29: 327–335.
  Article CAS PubMed Google Scholar
• Pigeon C, Ilyin G, Courselaud B et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 2001; 276: 7811–7819.
  Article CAS PubMed Google Scholar
• Shike H, Lauth X, Westerman ME et al. Bass hepcidin is a novel antimicrobial peptide induced by bacterial challenge. Eur J Biochem 2002; 269: 2232–2237.
  Article CAS PubMed Google Scholar
• Ashrafian H . Hepcidin: the missing link between hemochromatosis and infections. Infect Immun 2003; 71: 6693–6700.
  Article CAS PubMed PubMed Central Google Scholar
• Sebastiani G, Olien L, Gauthier S et al. Mapping of genetic modulators of natural resistance to infection with Salmonella typhimurium in wild-derived mice. Genomics 1998; 47: 180–186.
  Article CAS PubMed Google Scholar
• Ihaka RGR . R: a language for data analysis and graphics. J Comput Graph Stat 1996; 5: 299–314.
  Google Scholar
• Broman KW, Wu H, Sen S, Churchill GA . R/qtl: QTL mapping in experimental crosses. Bioinformatics 2003; 19: 889–890.
  Article CAS PubMed Google Scholar
• Miller A . Subset Selection in Regression. Chapman and Hall: New York, 2002.
  Book Google Scholar
• Scharz G . Estimating the dimension of a model. Ann Stat 1978; 6: 461–464.
  Article Google Scholar
• Davison ACHD . Bootstrap Methods and Their Application. 4th edn. Cambridge University Press: Cambridge, 1997.
  Book Google Scholar