- Liu D, Knapp JE . Hydrodynamics-based gene delivery. Curr Opin Mol Ther 2001; 3: 192–197.
CAS PubMed Google Scholar
- Wiethoff CM, Middaugh CR . Barriers to nonviral gene delivery. J Pharm Sci 2003; 92: 203–217.
Article CAS Google Scholar
- Glickman MH, Ciechanover A . The ubiquitin–proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 2002; 82: 373–428.
Article CAS Google Scholar
- Dantuma NP, Masucci MG . Stabilization signals: a novel regulatory mechanism in the ubiquitin/proteasome system. FEBS Lett 2002; 529: 22–26.
Article CAS Google Scholar
- Strous GJ, Govers R . The ubiquitin–proteasome system and endocytosis. J Cell Sci 1999; 112: 1417–1423.
CAS PubMed Google Scholar
- Dunlop R . Recent developments in the intracellular degradation of oxidized proteins. Free Radic Biol Med 2002; 33: 894–906.
Article CAS Google Scholar
- Carrard G, Bulteau AL, Petropoulos I, Friguet B . Impairment of proteasome structure and function in aging. Int J Biochem Cell Biol 2002; 34: 1461–1474.
Article CAS Google Scholar
- Sakamoto KM . Ubiquitin-dependent proteolysis: its role in human diseases and the design of therapeutic strategies. Mol Gen Metab 2002; 77: 44–56.
Article CAS Google Scholar
- Pagano M . Cell cycle regulation by the ubiquitin pathway. FASEB J 1997; 11: 1067–1075.
Article CAS Google Scholar
- Goldberg AL . Functions of the proteasome: the lysis at the end of the tunnel. Science 1995; 268: 522–523.
Article CAS Google Scholar
- Baumeister W, Cejka Z, Kania M, Seemuller E . The proteasome: a macromolecular assembly designed to confine proteolysis to a nanocompartment. Biol Chem 1997; 378: 121–130.
CAS PubMed Google Scholar
- Wlodawer A . Proteasome: a complex protease with a new fold and a distinct mechanism. Structure 1995; 3: 417–420.
Article CAS Google Scholar
- Dawson S et al. The 26S-proteasome: regulation and substration recognition. Mol Biol Rep 1997; 24: 39–44.
Article CAS Google Scholar
- Rivett AJ, Mason GF, Murray RJ, Reidlinger J . Regulation of proteasome structure and function. Mol Biol Rep 1997; 24: 99–102.
Article CAS Google Scholar
- Ben-Neriah Y . Regulatory functions of ubiquitination in the immune system. Nat Immun 2002; 3: 20–26.
Article CAS Google Scholar
- Duan D et al. Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus. J Clin Invest 2000; 105: 1573–1587.
Article CAS Google Scholar
- Goettsch S, Bayer P . Structural attributes in the conjugation of ubiquitin, SUMO and RUB to protein substrates. Front Biosci 2002; 7: a148–162.
Article CAS Google Scholar
- McKenzie DL, Kwok KY, Rice KG . A potent new class of reductively activated peptide gene delivery agents. J Biol Chem 2000; 275: 9970–9977.
Article CAS Google Scholar
- Bogyo M, Wang EW . Proteasome inhibitors: complex tools for a complex enzyme. Curr Top Microbiol Immunol 2002; 268: 185–208.
CAS PubMed Google Scholar
- Meng L et al. Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity. Proc Natl Acad Sci USA 1999; 96: 10403–10408.
Article CAS Google Scholar
- Almond JB, Cohen GM . The proteasome: a novel target for cancer chemotherapy. Leukemia 2002; 16: 433–443.
Article CAS Google Scholar
- Adams J et al. Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res 1999; 59: 2615–2622.
CAS PubMed Google Scholar
- Grimm LM et al. Proteasomes play an essential role in thymocyte apoptosis. EMBO 1996; 15: 3835–3844.
Article CAS Google Scholar
- Levitskaya J et al. Inhibition of antigen processing by the internal repeat region of the Epstein–Barr virus nuclear antigen-1. Nature 1995; 375: 685–688.
Article CAS Google Scholar
- Tanaka K, Tsurumi C . The 26S proteasome: subunits and functions. Mol Biol Rep 1997; 24: 3–11.
Article CAS Google Scholar
- Douar AM, Poulard K, Stockholm D, Danos O . Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradation. J Virol 2001; 75: 1824–1833.
Article CAS Google Scholar
- Adami RC, Rice KG . Metabolic stability of glutaraldehyde cross-linked peptide DNA condensates. J Pharm Sci 1999; 88: 739–746.
Article CAS Google Scholar
- Adami RC et al. Stability of peptide-condensed plasmid dna formulations. J Pharm Sci 1998; 87: 678–683.
Article CAS Google Scholar
- Levitskaya J et al. Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein–Barr virus nuclear antigen 1. Proc Natl Acad Sci USA 1997; 94: 12616–12621.
Article CAS Google Scholar
- Dantuma NP, Sharipo A, Masucci MG . Avoiding proteasomal processing: the case of EBNA1. Curr Top Microbiol Immun 2002; 269: 23–36.
CAS Google Scholar
- Dantuma NP et al. Inhibition of proteasomal degradation by the Gly-Ala repeat of Epstein–Barr virus is influenced by the length of the repeat and the strength of the degradation signal. Proc Natl Acad Sci USA 2000; 97: 8381–8385.
Article CAS Google Scholar
- Wadhwa MS et al. Peptide-mediated gene delivery: influence of peptide structure on gene expression. Bioconjugate Chem 1997; 8: 81–88.
Article CAS Google Scholar
- Mosmann T . Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immun Methods 1983; 65: 55–63.
Article CAS Google Scholar
- Rodgers KJ, Dean RT . Assessment of proteasome activity in cell lysates and tissue homogenates using peptide substrates. Int J Biochem Cell Biol 2003; 35: 716–727.
Article CAS Google Scholar
- Smith PK et al. Measurement of protein using bicinchoninic acid. Anal Biochem 1985; 150: 76–85.
Article CAS Google Scholar
- Terebesi J, Kwok KY, Rice KG . Iodinated plasmid DNA as a tool for studying gene delivery. Anal Biochem 1998; 263: 120–123.
Article CAS Google Scholar