The effect of sex, age and race on estimating percentage body fat from body mass index: The Heritage Family Study (original) (raw)
- Paper
- Published: 30 May 2002
- PR Stanforth1,
- J Gagnon3,
- T Rankinen4,
- AS Leon5,
- DC Rao6,
- JS Skinner7,
- C Bouchard4 &
- …
- JH Wilmore1
International Journal of Obesity volume 26, pages 789–796 (2002)Cite this article
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Abstract
Objective: To study the effects of sex, age and race on the relation between body mass index (BMI) and measured percent body fat (%fat).
Design: Cross-sectional validation study of sedentary individuals.
Subjects: The Heritage Family Study cohort of 665 black and white men and women who ranged in age from 17 to 65 y.
Measurements: Body density determined from hydrostatic weighing. Percentage body fat determined with gender and race-specific, two-compartment models. BMI determined from height and weight, and sex and race in dummy coded form.
Results: Polynomial regression showed that the relationship between %fat and BMI was quadratic for both men and women. A natural log transformation of BMI adjusted for the non-linearity. Test for homogeneity of log transformed BMI and gender showed that the male–female slopes were within random variance, but the intercepts differed. For the same BMI, the %fat of females was 10.4% higher than that of males. General linear models analysis of the women's data showed that age, race and race-by-BMI interaction were independently related to %fat. The same analysis applied to the men's data showed that %fat was not just a function of BMI, but also age and age-by-BMI interaction. Multiple regression analyses provided models that defined the bias.
Conclusions: These data and results published in the literature show that BMI and %fat relationship are not independent of age and gender. These data showed a race effect for women, but not men. The failure to adjust for these sources of bias resulted in substantial differences in the proportion of subjects defined as obese by measured %fat.
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Acknowledgements
The Heritage Family Study is supported by the National Heart, Lung and Blood Institute through the following grants: HL45670 (C Bouchard, PI); HL47323 (AS Leon, PI); HL47317 (DC Rao, PI); HL47327 (JS Skinner, PI); and HL47321 (JH Wilmore, PI). Claude Bouchard is partially supported by the George A Bray Chair in Nutrition. Credit is also given to the University of Minnesota Clinical Research Center, NIH Grant MO1-RR000400. Further, Art Leon is partially supported by the Henry L Taylor Professorship in Exercise Science and Health Enhancement. Thanks are expressed to all of the co-principal investigators, investigators, co-investigators, local project coordinators, research assistants, laboratory technicians, and secretaries who have contributed to this study (see Bouchard et al10). Finally, the Heritage consortium is very thankful to those hard-working families whose participation has made these data possible.
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Authors and Affiliations
- Department of Health and Kinesiology, Texas A&M University, College Station, Texas, USA
AS Jackson, PR Stanforth & JH Wilmore - Department of Health and Human Performance, University of Houston, Houston, Texas, USA
AS Jackson - Laboratory of Molecular Endocrinology, Laval University, Québec City, Québec, Canada
J Gagnon - Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
T Rankinen & C Bouchard - School of Kinesiology and Leisure Studies, University of Minnesota, Minneapolis, Minnesota, USA
AS Leon - Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri, USA
DC Rao - Department of Kinesiology, Indiana University, Bloomington, Indiana, USA
JS Skinner
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Jackson, A., Stanforth, P., Gagnon, J. et al. The effect of sex, age and race on estimating percentage body fat from body mass index: The Heritage Family Study.Int J Obes 26, 789–796 (2002). https://doi.org/10.1038/sj.ijo.0802006
- Received: 22 May 2001
- Revised: 28 November 2001
- Accepted: 09 January 2002
- Published: 30 May 2002
- Issue Date: 01 June 2002
- DOI: https://doi.org/10.1038/sj.ijo.0802006