The AFT024 stromal cell line supports long-term ex vivo maintenance of engrafting multipotent human hematopoietic progenitors (original) (raw)
Moore KA, Ema H, Lemischka IR . In vitro maintenance of highly purified, transplantable hematopoietic stem cells Blood 1997 89: 4337–4347 CASPubMed Google Scholar
Thiemann FT, Moore KA, Smogorzewska EM, Lemischka IR, Crooks GM . The murine stromal cell line AFT024 acts specifically on human CD34+CD38− progenitors to maintain primitive function and immunophenotype in vitroExp Hematol 1998 26: 612–619 CASPubMed Google Scholar
Punzel M, Moore KA, Lemischka IR, Verfaillie CM . The type of stromal feeder used in limiting dilution assays influences frequency and maintenance assessment of human long-term culture initiating cells Leukemia 1999 13: 92–97 ArticleCASPubMed Google Scholar
Punzel M, Wissink SD, Miller JS, Moore KA, Lemischka IR, Verfaillie CM . The myeloid-lymphoid initiating cell (ML-IC) assay assesses the fate of multipotent human progenitors in vitroBlood 1999 93: 3750–3756 CASPubMed Google Scholar
Punzel M, Gupta P, Roodell M, Mortari F, Verfaillie CM . Factor(s) secreted by AFT024 fetal liver cells following stimulation with human cytokines are important for human LTC-IC growth Leukemia 1999 13: 1079–1084 ArticleCASPubMed Google Scholar
Barker J, Verfaillie CM . A novel in vitro model of early human adult B lymphopoiesis that allows proliferation of pro-B cells and differentiation to mature B lymphocytes Leukemia 2000 14: 1614–1620 ArticleCASPubMed Google Scholar
Lewis ID, Verfaillie CM . Multi-lineage expansion potential of primitive hematopoietic progenitors. Superiority of umbilical cord blood compared to mobilized peripheral blood Exp Hematol 2000 28: 1087–1095 ArticleCASPubMed Google Scholar
Miller JS, McCullar V, Punzel M, Lemischka IR, Moore KA . Single adult human CD34(+)/Lin−/CD38(−) progenitors give rise to natural killer cells, B-lineage cells, dendritic cells, and myeloid cells Blood 1999 93: 96–106 CASPubMed Google Scholar
Gallacher L, Murdoch B, Wu DM, Karanu FN, Keeney M, Bhatia M . Isolation and characterization of human CD34(−)Lin(−) and CD34(+)Lin(−) hematopoietic stem cells using cell surface markers AC133 and CD7 Blood 2000 95: 2813–2820 CASPubMed Google Scholar
Oh IH, Lau A, Eaves CJ . During ontogeny primitive (CD34(+)CD38(−)) hematopoietic cells show altered expression of a subset of genes associated with early cytokine and differentiation responses of their adult counterparts Blood 2000 96: 4160–4168 CASPubMed Google Scholar
Tsuji T, Itoh K, Nishimura-Morita Y, Watanabe Y, Hirano D, Mori KJ, Yatsunami K . CD34high+ CD38(low/−) cells generated in a xenogenic coculture system are capable of both long-term hematopoiesis and multiple differentiation Leukemia 1999 13: 1409–1419 ArticleCASPubMed Google Scholar
Bhatia M, Wang JCY, Kapp U, Bonnet D, Dick JE . Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice Proc Natl Acad Sci USA 1997 94: 5320–5325 ArticleCASPubMedPubMed Central Google Scholar
Petzer AL, Zandstra PW, Piret JM, Eaves CJ . Differential cytokine effects on primitive (CD34+CD38−) human hematopoietic cells: novel responses to Flt3-ligand and thrombopoietin J Exp Med 1996 183: 2551–2558 ArticleCASPubMed Google Scholar
Hao QL, Shah AJ, Thiemann FT, Smogorzewska EM, Crooks GM . A functional comparison of CD34+ CD38− cells in cord blood and bone marrow Blood 1995 86: 3745–3753 CASPubMed Google Scholar
Issaad C, Croisille L, Katz A, Vainchenker W, Coulombel L . A murine stromal cell line allows the proliferation of very primitive human CD34++/CD38− progenitor cells in long-term cultures and semisolid assays Blood 1993 81: 2916–2924 CASPubMed Google Scholar
Terstappen LW, Huang S, Safford M, Lansdorp PM, Loken MR . Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38− progenitor cells Blood 1991 77: 1218–1227 CASPubMed Google Scholar
Wang X, Hong R, Nolta J . Extrathymic human T lymphocyte development and regulation in immune deficient mice Exp Hematol 2000 28: 1500 Article Google Scholar
Tsark EC, Dao MA, Wang X, Weinberg K, Nolta JA . IL-7 enhances the responsiveness of human T cells that develop in the bone marrow of athymic mice J Immunol 2001 166: 170–181 ArticleCASPubMed Google Scholar
Nolta JA, Hanley MB, Kohn DB . Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3: analysis of gene transduction of long-lived progenitors Blood 1994 83: 3041–3051 CASPubMed Google Scholar
Dao MA, Nolta JA . Use of the bnx/hu xenograft model of human hematopoiesis to optimize methods for retroviral-mediated stem cell transduction (review) Int J Mol Med 1998 1: 257–264 CASPubMed Google Scholar
Dao MA, Nolta JA . Immunodeficient mice as models of human hematopoietic stem cell engraftment Curr Opin Immunol 1999 11: 532–537 ArticleCASPubMed Google Scholar
Prochazka M, Gaskins HR, Shultz LD, Leiter EH . The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency Proc Natl Acad Sci USA 1992 89: 3290–3294 ArticleCASPubMedPubMed Central Google Scholar
Dao MA, Nolta JA . CD34: to select or not to select? That is the question Leukemia 2000 14: 773–776 ArticleCASPubMed Google Scholar
Dao MA, Shah AJ, Crooks GM, Nolta JA . Engraftment and retroviral marking of CD34+ and CD34+CD38− human hematopoietic progenitors assessed in immune-deficient mice Blood 1998 91: 1243–1255 CASPubMed Google Scholar
Nolta JA, Dao MA, Wells S, Smogorzewska EM, Kohn DB . Transduction of pluripotent human hematopoietic stem cells demonstrated by clonal analysis after engraftment in immune-deficient mice Proc Natl Acad Sci USA 1996 93: 2414–2419 ArticleCASPubMedPubMed Central Google Scholar
Dao MA, Pepper KA, Nolta JA . Long-term cytokine production from engineered primary human stromal cells influences human hematopoiesis in an in vivo xenograft model Stem Cells 1997 15: 443–454 ArticleCASPubMedPubMed Central Google Scholar
Arakawa-Hoyt J, Dao MA, Thiemann F, Hao QL, Ertl DC, Weinberg KI, Crooks GM, Nolta JA . The number and generative capacity of human B lymphocyte progenitors, measured in vitro and in vivo, is higher in umbilical cord blood than in adult or pediatric bone marrow Bone Marrow Transplant 1999 24: 1167–1176 ArticleCASPubMed Google Scholar
Bhatia M, Bonnet D, Murdoch B, Gan OI, Dick JE . A newly discovered class of human hematopoietic cells with SCID-repopulating activity (see comments) Nat Med 1998 4: 1038–1045 ArticleCASPubMed Google Scholar
Fujisaki T, Berger MG, Rose-John S, Eaves CJ . Rapid differentiation of a rare subset of adult human lin(−)CD34(−)CD38(−) cells stimulated by multiple growth factors in vitroBlood 1999 94: 1926–1932 CASPubMed Google Scholar
Dao MA, Yu XJ, Nolta JA . Clonal diversity of primitive human hematopoietic progenitors following retroviral marking and long-term engraftment in immune-deficient mice Exp Hematol 1997 25: 1357–1366 CASPubMed Google Scholar
Dorrell C, Gan OI, Pereira DS, Hawley RG, Dick JE . Expansion of human cord blood CD34(+)CD38(−) cells in ex vivo culture during retroviral transduction without a corresponding increase in SCID repopulating cell (SRC) frequency: dissociation of SRC phenotype and function Blood 2000 95: 102–110 CASPubMed Google Scholar
Bhatia M, Bonnet D, Kapp U, Wang JC, Murdoch B, Dick JE . Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture J Exp Med 1997 186: 619–624 ArticleCASPubMedPubMed Central Google Scholar
Moore KA, Pytowski B, Witte L, Hicklin D, Lemischka IR . Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs Proc Natl Acad Sci USA 1997 94: 4011–4016 ArticleCASPubMedPubMed Central Google Scholar
Smas CM, Sul HS . Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation Cell 1993 73: 725–734 ArticleCASPubMed Google Scholar
Laborda J, Sausville EA, Hoffman T, Notario V . dlk, a putative mammalian homeotic gene differentially expressed in small cell lung carcinoma and neuroendocrine tumor cell line J Biol Chem 1993 268: 3817–3820 CASPubMed Google Scholar
Shah AJ, Smogorzewska EM, Hannum C, Crooks GM . Flt3 ligand induces proliferation of quiescent human bone marrow CD34+CD38− cells and maintains progenitor cells in vitroBlood 1996 87: 3563–3570 CASPubMed Google Scholar
Hao QL, Thiemann FT, Petersen D, Smogorzewska EM, Crooks GM . Extended long-term culture reveals a highly quiescent and primitive human hematopoietic progenitor population Blood 1996 88: 3306–3313 CASPubMed Google Scholar
Hao QL, Smogorzewska EM, Barsky LW, Crooks GM . In vitro identification of single CD34+CD38− cells with both lymphoid and myeloid potential Blood 1998 91: 4145–4151 CASPubMed Google Scholar
Verfaillie CM, Almeida-Porada G, Wissink S, Zanjani ED . Kinetics of engraftment of CD34(−) and CD34(+) cells from mobilized blood differs from that of CD34(−) and CD34(+) cells from bone marrow Exp Hematol 2000 28: 1071–1079 ArticleCASPubMed Google Scholar
Nakamura Y, Ando K, Chargui J, Kawada H, Sato T, Tsuji T, Hotta T, Kato S . Ex vivo generation of CD34(+) cells from CD34(−) hematopoietic cells Blood 1999 94: 4053–4059 CASPubMed Google Scholar
Sato T, Laver JH, Ogawa M . Reversible expression of CD34 by murine hematopoietic stem cells Blood 1999 94: 2548–2554 CASPubMed Google Scholar
Dao MA, Nolta JA . Reversibility of CD34 expression on human stem cells that retain the capacity for secondary reconstitution Blood 2000 96: 581a Google Scholar