Aptamer-mediated ‘turn-off/turn-on’ nanozyme activity of gold nanoparticles for kanamycin detection (original) (raw)
* Corresponding authors
a Ian Potter NanoBioSensing Facility, NanoBiotechnology Research Laboratory, School of Applied Science, RMIT University, GPO Box 2476V, Melbourne VIC 3001, Australia
E-mail: vipul.bansal@rmit.edu.au
Fax: +61 3 99253747
Tel: +61 3 99252121
b Centre for Biodesign and Diagnostics, Translational Health Science and Technology Research Institute, Gurgaon, Haryana 247667, India
E-mail: tarun@thsti.res.in
c Department of Biotechnology, Siddaganga Institute of Technology, Tumkur, Karnataka 572103, India
Abstract
A new ultrafast and highly sensitive ‘turn-off/turn-on’ biosensing approach that combines the intrinsic peroxidase-like activity of gold nanoparticles (GNPs) with the high affinity and specificity of a ssDNA aptamer is presented for the efficient detection of a model small molecule kanamycin.
- This article is part of the themed collection:ChemComm 60th Anniversary Historic Papers from India
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Article information
DOI
https://doi.org/10.1039/C4CC07275H
Article type
Communication
Submitted
15 Sep 2014
Accepted
30 Sep 2014
First published
06 Oct 2014
Download Citation
Chem. Commun., 2014,50, 15856-15859
Permissions
Aptamer-mediated ‘turn-off/turn-on’ nanozyme activity of gold nanoparticles for kanamycin detection
T. K. Sharma, R. Ramanathan, P. Weerathunge, M. Mohammadtaheri, H. K. Daima, R. Shukla and V. Bansal,Chem. Commun., 2014, 50, 15856DOI: 10.1039/C4CC07275H
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