Nanotechnology-based combinatorial phototherapy for enhanced cancer treatment (original) (raw)

* Corresponding authors

a School of Pharmacy, Pharm-X Center, Shanghai Jiao Tong Univeristy, Shanghai, China
E-mail: xuexd@sjtu.edu.cn

b Laboratory of Clinical Smart Nanotechnologies, Institute for Regenerative Medicine, Sechenov University, Moscow, Russia

c CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Chinese Academy of Sciences, National Center for Nanoscience and Technology of China, Beijing, China
E-mail: liangxj@nanoctr.cn

Abstract

Nanotechnology-based phototherapy has attracted enormous attention to cancer treatment owning to its non-invasiveness, high controllability and accuracy. Given the fast development of anti-tumor strategies, we summarize various examples of multifunctional nanosystems to highlight the recent advances in nanotechnology-based combinatorial phototherapy towards improving cancer treatment. The limitations of the monotherapeutic approach and the superiority of the photo-involved combinatorial strategies are discussed in each part. The future breakthroughs and clinical perspectives of combinatorial phototherapy are also outlooked. Our perspectives may inspire researchers to develop more effective phototherapy-based cancer-treating approaches.

Graphical abstract: Nanotechnology-based combinatorial phototherapy for enhanced cancer treatment

This article is Open Access

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Article information

DOI

https://doi.org/10.1039/D1RA09067D

Article type

Review Article

Submitted

15 Dec 2021

Accepted

19 Mar 2022

First published

04 Apr 2022

This article is Open Access

Download Citation

RSC Adv., 2022,12, 9725-9737

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