Inorganic-based biomaterials for rapid hemostasis and wound healing (original) (raw)
* Corresponding authors
a State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, No. 1295 Dingxi Road, Shanghai 200050, People's Republic of China
E-mail: zhuyufang@mail.sic.ac.cn, chengtiewu@mail.sic.ac.cn
b Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, No. 19(A) Yuquan Road, Beijing 100049, People's Republic of China
Abstract
The challenge for the treatment of severe traumas poses an urgent clinical need for the development of biomaterials to achieve rapid hemostasis and wound healing. In the past few decades, active inorganic components and their derived composites have become potential clinical products owing to their excellent performances in the process of hemorrhage control and tissue repair. In this review, we provide a current overview of the development of inorganic-based biomaterials used for hemostasis and wound healing. We highlight the methods and strategies for the design of inorganic-based biomaterials, including 3D printing, freeze-drying, electrospinning and vacuum filtration. Importantly, inorganic-based biomaterials for rapid hemostasis and wound healing are presented, and we divide them into several categories according to different chemistry and forms and further discuss their properties, therapeutic mechanisms and applications. Finally, the conclusions and future prospects are suggested for the development of novel inorganic-based biomaterials in the field of rapid hemostasis and wound healing.
- This article is part of the themed collections:Most popular 2023 chemical biology articles, 2023 Chemical Science Perspective & Review Collection and 2023 Chemical Science HOT Article Collection
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Article information
DOI
https://doi.org/10.1039/D2SC04962G
Article type
Review Article
Submitted
06 Sep 2022
Accepted
07 Nov 2022
First published
30 Nov 2022
This article is Open Access
All publication charges for this article have been paid for by the Royal Society of Chemistry
Download Citation
Chem. Sci., 2023,14, 29-53
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Inorganic-based biomaterials for rapid hemostasis and wound healing
Y. Zheng, J. Wu, Y. Zhu and C. Wu,Chem. Sci., 2023, 14, 29DOI: 10.1039/D2SC04962G
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