DNER as key molecule for cerebellar maturation (original) (raw)

Access this article

Log in via an institution

Subscribe and save

• Get 10 units per month
• Download Article/Chapter or eBook
• 1 Unit = 1 Article or 1 Chapter
• Cancel anytime Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

1. Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: Cell fate control and signal integration in development. Science. 1999;284:770–6.
   Article PubMed CAS Google Scholar
2. Mumm JS, Kopan R. Notch signaling: From the outside in. Dev Biol. 2000;228:151–65.
   Article PubMed CAS Google Scholar
3. Struhl G, Adachi A. Requirements for presenilin-dependent cleavage of Notch and other transmembrane proteins. Mol Cell. 2000;6:625–36.
   Article PubMed CAS Google Scholar
4. Ramain P, Khechumian K, Seugnet L, Arbogast N, Ackermann C, Heitzler P. Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate. Curr Biol. 2001;11:1729–38.
   Article PubMed CAS Google Scholar
5. De Strooper B, Annaert W, Cupers P, Saftig P, Craessaerts K, Mumm JS, Schroeter EH, Schrijvers V, Wolfe MS, Rayk WJ, Goatek A, Kopan R. A presenillin-1-dependent (-secretase-like protease mediates release of Notch intracellular domain. Nature. 1999;398:518–22.
   Article PubMed Google Scholar
6. Kageyama R, Ohtsuka T, Hatakeyama J, Ohsawa R. Roles of bHLH genes in neural stem cell differentiation. Exp Cell Res. 2005;306:343–8.
   Article PubMed Google Scholar
7. Wu L, Aster JC, Blacklow SC, Lake R, Artavanis-Tsakonas S, Griffin JD. MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for Notch receptors. Nat Genet. 2000;26:484–9.
   Article PubMed CAS Google Scholar
8. Bailey AM, Posakony JW. Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity. Genes Dev. 1995;9: 2609–22.
   Article PubMed CAS Google Scholar
9. Matsuno K, Ito M, Hori K, Miyashita F, Suzuki S, Kishi N, Artavanis-Tsakonas S, Okano H. Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling. Development. 2002;129:1049–59.
   PubMed CAS Google Scholar
10. Liu WH, Lai MZ. Deltex regulates T-cell activation by targeted degradation of active MEKK1. Mol Cell Biol. 2005;25:1367–78.
    Article PubMed Google Scholar
11. Anderson DJ. Stem cells and pattern formation in the nervous system: The possible versus the actual. Neuron. 2001;30: 19–35.
    Article PubMed CAS Google Scholar
12. Eiraku M, Hirata Y, Takeshima H, Hirano T, Kengaku M. Delta/Notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neurons. J Biol Chem. 2002;277:25400–07.
    Article PubMed CAS Google Scholar
13. Nishizumi H, Komiyama T, Miyabayashi T, Sakano S, Sakano H. BET, a novel neuronal transmembrane protein with multiple EGF-like motifs. NeuroReport. 2002;13: 909–15.
    Article PubMed CAS Google Scholar
14. Handford PA, Mayhew M, Baron M, Winship PR, Campbell ID, Brownlee GG. Key residues involved in calcium-binding motifs in EGF-like domains. Nature. 1991;351:164–7.
    Article PubMed CAS Google Scholar
15. Bonifacino JS, Traub LM. Signals for sorting of transmem-brane proteins to endosomes and lysosomes. Annu Rev Biochem. 2003;72:395–447.
    Article PubMed CAS Google Scholar
16. Eiraku M, Tohgo A, Ono K, Kaneko M, Fujishima K, Hirano T, Kengaku M. DNER acts as a neuron-specific Notch ligand during Bergmann glial development. Nat Neurosci. 2005;8:873–80.
    PubMed Google Scholar
17. Shawber C, Nofziger D, Hsieh JJ, Lindsell C, Bogler O, Hayward D, Weinmaster G. Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway. Development. 1996;122:3765–73.
    PubMed CAS Google Scholar
18. Patten BA, Peyrin JM, Weinmaster G, Corfas G. Sequential signaling through Notch1 and erbB receptors mediates radial glia differentiation. J Neurosci. 2003;23:6132–40.
    PubMed CAS Google Scholar
19. Tohgo A, Eiraku M, Miyazaki T, Miura E, Kawaguchi S, Nishi M, Watanabe M, Hirano T, Kengaku M, Takeshima H. Impaired cerebellar functions in mutant mice lacking DNER. Mol Cell Neurosci. 2005 in press.
20. Watase K, Hashimoto K, Kano M, Yamada K, Watanabe M, Inoue Y, Okuyama S, Sakagawa T, Ogawa S, Kawashima N, Hori S, Takimoto M, Wada K, Tanaka K. Motor discoordination and increased susceptibility to cerebellar injury in GLAST mutant mice. Eur J Neurosci. 1998;10:976–88.
    Article PubMed CAS Google Scholar
21. Lordkipanidze T, Dunaevsky A. Purkinje cell dendrites grow in alignment with Bergmann glia. Glia. 2005;51: 229–34.
    Article PubMed Google Scholar

Download references