Tbe complete nudeotide sequences of the cloned hepatitis B vims DNA; subtype adr and adw (original) (raw)
Journal Article
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Biotechnology Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.,
Jusohonmachi 2-17-85, Yodogawa–ku, Osaka 532
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,
*
Biotechnology Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.,
Jusohonmachi 2-17-85, Yodogawa–ku, Osaka 532
Search for other works by this author on:
,
*
Biotechnology Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.,
Jusohonmachi 2-17-85, Yodogawa–ku, Osaka 532
Search for other works by this author on:
,
*
Biotechnology Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.,
Jusohonmachi 2-17-85, Yodogawa–ku, Osaka 532
Search for other works by this author on:
,
*
Biotechnology Laboratories, Central Research Division, Takeda Chemical Industries, Ltd.,
Jusohonmachi 2-17-85, Yodogawa–ku, Osaka 532
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Tokyo Metropolitan Institute of Medical Science
Honkomagome 3-18-22, Bunkyo–ku, Tokyo 113, Japan
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Received:
12 January 1983
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Yoshitaka Ono, Haruo Onda, Reiko Sasada, Koichi Igarashi, Yukdo Sugino, Kusuya Nishioka, Tbe complete nudeotide sequences of the cloned hepatitis B vims DNA; subtype adr and adw, Nucleic Acids Research, Volume 11, Issue 6, 25 March 1983, Pages 1747–1757, https://doi.org/10.1093/nar/11.6.1747
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Abstract
The complete nucleotide sequences of two different subtypes (adr and adw) of hepatitis B virus (HBV) DNA cloned in E. coli were determined. The sequence of the viral genome of the adr clone was 3188 nucleotides long, and that of the adw clone was 3200 nucleotides long. The adr and adw clones differed from the reported cloned ayw HBV DNA (3182 nucleotides long) in 11.2% and 10.0% of nucleotides, respectively. Heterogeneity of the HBV genome in the clones with the same subtype was observed.
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