Similarity of reverse transcriptase-like sequences of viruses, transposable elements, and mitochondrial introns. (original) (raw)
Journal Article
,
Search for other works by this author on:
Search for other works by this author on:
Published:
01 November 1988
PDF Cite
Y Xiong, T H Eickbush, Similarity of reverse transcriptase-like sequences of viruses, transposable elements, and mitochondrial introns., Molecular Biology and Evolution, Volume 5, Issue 6, 1 July 1988, Pages 675–690, https://doi.org/10.1093/oxfordjournals.molbev.a040521
Close
Navbar Search Filter Mobile Enter search term Search
Abstract
Sequences similar to reverse transcriptase (RT) of retroviruses have been found in certain DNA viruses, mitochondrial intron sequences, and a wide variety of transposable elements. While total amino acid similarity between these diverse elements is quite low, we have identified seven regions, consisting of 182 amino acids, that are common to all elements. Highly conserved residues identified in each of these regions are diagnostic for the identification and alignment of these and for future RT-like sequences. Using both the neighbor-joining and the unweighted-pair-group methods, we have derived a probable phylogenetic tree for all RT-containing elements. These elements can be divided into two major groups. Retroviruses and DNA viruses whose propagation involves an RNA intermediate are grouped with a series of transposable elements containing long terminal repeats (LTRs). The second group is made up of RT-containing sequences of fungal mitochondrial introns and a series of transposable elements that lack LTRs. The transposable elements, copia and Ty, were found to be the most difficult to position on the phylogenetic tree, as a result of their higher rate of sequence divergence. The data are most consistent with their being distant members of the LTR group (retroviruses/LTR retrotransposons).
This content is only available as a PDF.
Citations
Views
Altmetric
Metrics
Total Views 378
59 Pageviews
319 PDF Downloads
Since 12/1/2016
| Month: | Total Views: |
|---|---|
| December 2016 | 2 |
| February 2017 | 3 |
| March 2017 | 7 |
| April 2017 | 11 |
| May 2017 | 10 |
| June 2017 | 4 |
| July 2017 | 3 |
| August 2017 | 2 |
| September 2017 | 3 |
| October 2017 | 5 |
| November 2017 | 4 |
| December 2017 | 2 |
| January 2018 | 10 |
| February 2018 | 1 |
| March 2018 | 5 |
| April 2018 | 6 |
| June 2018 | 1 |
| July 2018 | 1 |
| August 2018 | 1 |
| September 2018 | 1 |
| October 2018 | 2 |
| November 2018 | 5 |
| December 2018 | 1 |
| February 2019 | 4 |
| March 2019 | 5 |
| April 2019 | 1 |
| June 2019 | 3 |
| July 2019 | 3 |
| August 2019 | 3 |
| November 2019 | 7 |
| February 2020 | 1 |
| March 2020 | 2 |
| April 2020 | 1 |
| May 2020 | 1 |
| June 2020 | 1 |
| July 2020 | 3 |
| August 2020 | 4 |
| September 2020 | 5 |
| October 2020 | 5 |
| November 2020 | 7 |
| December 2020 | 7 |
| January 2021 | 3 |
| February 2021 | 5 |
| March 2021 | 6 |
| April 2021 | 6 |
| May 2021 | 8 |
| June 2021 | 6 |
| July 2021 | 3 |
| August 2021 | 3 |
| September 2021 | 6 |
| October 2021 | 10 |
| November 2021 | 6 |
| December 2021 | 4 |
| January 2022 | 5 |
| February 2022 | 1 |
| March 2022 | 4 |
| April 2022 | 3 |
| May 2022 | 3 |
| June 2022 | 3 |
| August 2022 | 4 |
| September 2022 | 4 |
| October 2022 | 3 |
| November 2022 | 6 |
| December 2022 | 4 |
| January 2023 | 4 |
| February 2023 | 6 |
| March 2023 | 3 |
| April 2023 | 4 |
| May 2023 | 6 |
| June 2023 | 1 |
| July 2023 | 3 |
| August 2023 | 8 |
| September 2023 | 1 |
| October 2023 | 5 |
| November 2023 | 6 |
| December 2023 | 5 |
| January 2024 | 5 |
| February 2024 | 12 |
| March 2024 | 10 |
| April 2024 | 13 |
| May 2024 | 1 |
| June 2024 | 6 |
| July 2024 | 10 |
| August 2024 | 4 |
| September 2024 | 4 |
| October 2024 | 2 |
×
Email alerts
Email alerts
Citing articles via
More from Oxford Academic