Restriction-map variation associated with the G6PD polymorphism in natural populations of Drosophila melanogaster. (original) (raw)

Journal Article

,

Search for other works by this author on:

,

Search for other works by this author on:

,

Search for other works by this author on:

Search for other works by this author on:

• PDF
• Split View
• • Article contents
  • Figures & tables
  • Video
  • Audio
  • Supplementary Data
• Cite

Cite

W F Eanes, J W Ajioka, J Hey, C Wesley, Restriction-map variation associated with the G6PD polymorphism in natural populations of Drosophila melanogaster., Molecular Biology and Evolution, Volume 6, Issue 4, Jul 1989, Pages 384–397, https://doi.org/10.1093/oxfordjournals.molbev.a040555
Close

Navbar Search Filter Mobile Enter search term Search

Abstract

Restriction-map variation was studied in 126 copies of the G6pd region in X chromosome lines of Drosophila melanogaster from North America, Europe, and Africa. Special attention was focused on the distribution of variation relative to the geographically variable polymorphism for two electrophoretic variants. Nucleotide heterozygosity as determined by eight six-cutter restriction enzymes for the 13-kb region is estimated, on the basis of the worldwide sample, to be 0.065%, which is the lowest value reported for any comparable region in the D. melanogaster genome. Significant linkage disequilibrium between electrophoretic alleles and restriction-site variation is observed for several sites. In contrast to published studies of other genetic regions, there are large insertions that reach significant frequencies and are found across considerable geographic distances. There is a clustering of this variation inside the first large intervening sequence of the G6PD gene.

This content is only available as a PDF.

Citations

Views

Altmetric

Metrics

Total Views 69

5 Pageviews

64 PDF Downloads

Since 12/1/2016

×

Email alerts

Email alerts

Citing articles via

• Latest

• Most Read

• Most Cited

More from Oxford Academic