Bunyaviridae (original) (raw)
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Intervirology (1980) 14 (3-4): 125–143.
Citation
D.H.L. Bishop, C.H. Calisher, J. Casals, M.P. Chumakov, S.Ya. Gaidamovich, C. Hannoun, D.K. Lvov, I.D. Marshall, N. Oker-Blom, R.F. Pettersson, J.S. Porterfield, P.K. Russell, R.E. Shope, E.G. Westaway; Bunyaviridae. _Intervirology 31 December 1980; 14 (3-4): 125–143. https://doi.org/10.1159/000149174
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Abstract
The family Bunyaviridae comprises over 200 viruses (serotypes, subtypes, and varieties) that infect vertebrates and/or invertebrates. Four genera of viruses have been defined (Bunyavirus, Nairovirus, Phlebovirus, and Uukuvirus). The main characteristics of the member viruses are: (i) the virus particles are for the most part uniformly spherical, 80–110 nm in diameter, and possess a unit membrane envelope from which protrude polypeptide spikes 5–10 nm long; (ii) the viruses have three helical nucleocapsids, often in the form of supercoiled circles, each consisting of a single species of single-stranded RNA, a major nucleocapsid polypeptide, N, and at least in some cases minor amounts of a large polypeptide which may be a transcriptase component; (iii) the genome is composed of three species of RNA (L, large; M, medium; and S, small), organized in end-hydrogen bonded circular structures; (iv) most viruses have three major virion polypeptides (N, and two surface polypeptides, designated Gl and G2); (v) for at least some member viruses, the virions have been shown to contain an RNA-directed RNA polymerase, believed to be responsible for the synthesis of viral complementary mRNA, so that bunyaviruses are considered to be negative-stranded viruses; (vi) at least some bunyaviruses are capable of heterologous virus genome segment reassortment and can form recombinant viruses at high or low frequency; (vii) viruses appear to mature primarily at smooth membrane surfaces and accumulate in Golgi vesicles and saccules, or nearby; (viii) transovarial, venereal and/or transstadial transmission in arthropods has been shown to occur for some members of the family.
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© 1980 S. Karger AG, Basel
1980
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