- Lee JE, Lowy AM, Thompson WA, et al. Association of gastric adenocarcinoma with the HLA class II gene DQB10301. Gastroenterology 1996; 111:426–32
Article PubMed CAS Google Scholar
- Ogoshi K, Tajima T, Mitomi T, Tsuji K. HLA antigens are candidate markers for prediction of lymph node metastasis in gastric cancer. Clin Exp Metastasis 1996; 14:277–81
PubMed CAS Google Scholar
- Nabeta Y, Sahara H, Suzuki K, et al. Induction of cytotoxic T lymphocytes from peripheral blood of human histocompatibility antigen (HLA)-A31(+) gastric cancer patients by in vitro stimulation with antigenic peptide of signet ring cell carcinoma. Jpn J Cancer Res 2000; 91:616–21
PubMed CAS Google Scholar
- Kono K, Takahashi A, Amemiya H, et al. Frequencies of HER-2/neu overexpression relating to HLA haplotype in patients with gastric cancer. Int J Cancer 2002; 98:216–20
Article PubMed CAS Google Scholar
- Lo SS, Lee YJ, Wu CW, Liu CJ, Huang JW, Lui WY. The increase of MICA gene A9 allele associated with gastric cancer and less schirrous change. Br J Cancer 2004; 90:1809–13
PubMed CAS Google Scholar
- Maines MD. Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J 1988; 2:2557–68
PubMed CAS Google Scholar
- Motterlini R, Foresti R, Bassi R, Calabrese V, Clark JE, Green CJ. Endothelial heme oxygenase-1 induction by hypoxia. Modulation by inducible nitric-oxide synthase and S-nitrosothiols. J Biol Chem 2000; 275:13613–20
Article PubMed CAS Google Scholar
- Shibahara S. Regulation of heme oxygenase gene expression. Semin Hematol 1988; 25:370–6
PubMed CAS Google Scholar
- Keyse SM, Tyrrell RM. Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proc Natl Acad Sci USA 1989; 86:99–103
Article PubMed CAS Google Scholar
- Oguro T, Hayashi M, Numazawa S, Asakawa K, Yoshida T. Heme oxygenase-1 gene expression by a glutathione depletor, phorone, mediated through AP-1 activation in rats. Biochem Biophys Res Commun 1996; 221:259–65
Article PubMed CAS Google Scholar
- Doi K, Akaike T, Fujii S, et al. Induction of haem oxygenase-1 nitric oxide and ischaemia in experimental solid tumours and implications for tumour growth. Br J Cancer 1999; 80:1945–54
Article PubMed CAS Google Scholar
- Maines MD, Abrahamsson PA. Expression of heme oxygenase-1 (HSP32) in human prostate: normal, hyperplastic, and tumor tissue distribution. Urology 1996; 47:727–33
Article PubMed CAS Google Scholar
- Goodman AI, Choudhury M, da Silva JL, Schwartzman ML, Abraham NG. Overexpression of the heme oxygenase gene in renal cell carcinoma. Proc Soc Exp Biol Med 1997; 214:54–61
PubMed CAS Google Scholar
- Liu ZM, Chen GG, Ng EK, Leung WK, Sung JJ, Chung SC. Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells. Oncogene 2004; 23:503–13
Article PubMed CAS Google Scholar
- Fang J, Sawa T, Akaike T, et al. In vivo antitumor activity of pegylated zinc protoporphyrin: targeted inhibition of heme oxygenase in solid tumor. Cancer Res 2003; 63:3567–74
PubMed CAS Google Scholar
- Sunamura M, Duda DG, Ghattas MH, et al. Heme oxygenase-1 accelerates tumor angiogenesis of human pancreatic cancer. Angiogenesis 2003; 6:15–24
Article PubMed CAS Google Scholar
- Kutty RK, Kutty G, Rodriguez IR, Chader GJ, Wiggert B. Chromosomal localization of the human heme oxygenase genes: heme oxygenase-1 (HMOX1) maps to chromosome 22q12 and heme oxygenase-2 (HMOX2) maps to chromosome 16p13.3. Genomics 1994; 20:513–6
Article PubMed CAS Google Scholar
- Lavrovsky Y, Schwartzman ML, Levere RD, Kappas A, Abraham NG. Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene. Proc Natl Acad Sci USA 1994; 91: 5987–91
Article PubMed CAS Google Scholar
- Silverman EK, Chapman HA, Drazen JM, et al. Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis. Am J Respir Crit Care Med 1998; 157:1770–8
PubMed CAS Google Scholar
- Ono K, Mannami T, Iwai N. Association of a promoter variant of the haeme oxygenase-1 gene with hypertension in women. J Hypertens 2003; 21:1497–503
Article PubMed CAS Google Scholar
- Kaneda H, Ohno M, Taguchi J, et al. Heme oxygenase-1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors. Arterioscler Thromb Vasc Biol 2002; 22:1680–5
Article PubMed CAS Google Scholar
- Chen YH, Lin SJ, Lin MW, et al. Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients. Hum Genet 2002; 111:1–8
Article PubMed CAS Google Scholar
- Baan C, Peeters A, Lemos F, et al. Fundamental role for HO-1 in the self-protection of renal allografts. Am J Transplant 2004; 4:811–88
Article PubMed CAS Google Scholar
- Exner M, Bohmig GA, Schillinger M, et al. Donor heme oxygenase-1 genotype is associated with renal allograft function. Transplantation 2004; 77:538–42
Article PubMed CAS Google Scholar
- Denschlag D, Marculescu R, Unfried G, et al. The size of a microsatellite polymorphism of the haem oxygenase 1 gene is associated with idiopathic recurrent miscarriage. Mol Hum Reprod 2004; 10:211–4
Article PubMed CAS Google Scholar
- Kimpara T, Takeda A, Watanabe K, et al. Microsatellite polymorphism in the human heme oxygenase-1 gene promoter and its application in association studies with Alzheimer and Parkinson disease. Hum Genet 1997; 100:145–7
Article PubMed CAS Google Scholar
- Hirai H, Kubo H, Yamaya M, et al. Microsatellite polymorphism in heme oxygenase-1 gene promoter is associated with susceptibility to oxidant-induced apoptosis in lymphoblastoid cell lines. Blood 2003; 102:1619–21
Article PubMed CAS Google Scholar
- Kanai M, Akaba K, Sasaki A, et al. Neonatal hyperbilirubinemia in Japanese neonates: analysis of the heme oxygenase-1 gene and fetal hemoglobin composition in cord blood. Pediatr Res 2003; 54:165–71
Article PubMed CAS Google Scholar
- Yamada N, Yamaya M, Okinaga S, Nakayama K, Sekizawa K, Shibahara S, Sasaki H. Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. Am J Hum Genet 2000; 66:187–95
Article PubMed CAS Google Scholar
- Kikuchi A, Yamaya M, Suzuki S, et al. Association of susceptibility to the development of lung adenocarcinoma with the heme oxygenase-1 gene promoter polymorphism. Hum Genet 2005; 116:354–60
Article PubMed CAS Google Scholar
- Chang KW, Lee TC, Yeh WI, Chung MY, Liu CJ, Chi LY, Lin SC. Polymorphism in heme oxygenase-1 (HO-1) promoter is related to the risk of oral squamous cell carcinoma occurring on male areca chewers. Br J Cancer 2004; 91:1551–5
Article PubMed CAS Google Scholar
- Japanese Research Society for Gastric Cancer. Japanese classification of gastric carcinoma, 1st English edn. Tokyo: Kanehara Shuppan, 1995
Google Scholar
- Agoresti A. An Introduction to Categorical Data Analysis. New York: Wiley, 1996: p. 24
Google Scholar
- Exner M, Minar E, Wagner O, Schillinger M. The role of heme oxygenase-1 promoter polymorphisms in human disease. Free Radic Biol Med 2004; 37:1097–104
Article PubMed CAS Google Scholar
- Tulis DA, Durante W, Peyton KJ, Evans AJ, Schafer AI. Heme oxygenase-1 attenuates vascular remodeling following balloon injury in rat carotid arteries. Atherosclerosis 2001; 155:113–22
Article PubMed CAS Google Scholar
- Duckers HJ, Boehm M, True AL, et al. Heme oxygenase-1 protects against vascular constriction and proliferation. Nat Med 2001; 7:693–8
Article PubMed CAS Google Scholar
- Ishikawa K, Sugawara D, Wang X, Suzuki K, Itabe H, Maruyama Y, Lusis AJ. Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice. Circ Res 2001; 88:506–12
PubMed CAS Google Scholar
- Tenhunen R, Marver HS, Schmid R. Microsomal heme oxygenase. Characterization of the enzyme. J Biol Chem 1969; 244:6388–94
CAS Google Scholar
- Stocker R, Yamamoto Y, McDonagh AF, Glazer AN, Ames BN. Bilirubin is an antioxidant of possible physiological importance. Science 1987; 235:1043–6
Article PubMed CAS Google Scholar
- Balla G, Jacob HS, Balla J, et al. Ferritin: a cytoprotective antioxidant strategem of endothelium. J Biol Chem 1992; 267:18148–53
PubMed CAS Google Scholar
- Verma A, Hirsch DJ, Glatt CE, Ronnett GV, Snyder SH. Carbon monoxide: a putative neural messenger. Science 1993; 259:381–4
Article PubMed CAS Google Scholar
- Exner M, Schillinger M, Minar E, et al. Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with restenosis after percutaneous transluminal angioplasty. J Endovasc Ther 2001; 8:433–40
Article PubMed CAS Google Scholar
- Furchgott RF, Jothianandan D. Endothelium-dependent, -independent vasodilation involving cyclic GMP: relaxation induced by nitric oxide, carbon monoxide and light. Blood Vessels 1991; 28:52–61
PubMed CAS Google Scholar
- Brune B, Ullrich V. Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. Mol Pharmacol 1987; 32:497–504
PubMed CAS Google Scholar
- Morita T, Perrella MA, Lee ME, Kourembanas S. Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc Natl Acad Sci USA 1995; 92:1475–9
Article PubMed CAS Google Scholar
- Wang R, Wu L, Wang Z. The direct effect of carbon monoxide on KCa channels in vascular smooth muscle cells. Pflugers Arch 1997; 434:285–91
Article PubMed CAS Google Scholar
- Correa P, Haenszel W, Cuello C, Tannenbaum S, Archer M. A model for gastric cancer epidemiology. Lancet 1975; 2:58–60
Article PubMed CAS Google Scholar
- Meining A, Riedl B, Stolte M. Features of gastritis predisposing to gastric adenoma and early gastric cancer. J Clin Pathol 2002; 55:770–3
Article PubMed CAS Google Scholar
- Coma del Corral MJ, Pardo-Mindan FJ, Razquin S, Ojeda C. Risk of cancer in patients with gastric dysplasia. Follow-up study of 67 patients. Cancer 1990; 65:2078–85
Google Scholar