Ras and Gpa2 Mediate One Branch of a Redundant Glucose Signaling Pathway in Yeast (original) (raw)

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Figure 2

Expression Patterns of Clustered Genes

Diagrams show the patterns of expression of genes in the classes (Roman numerals) listed in Table 1, which were clustered as described in Materials and Methods. Each line represents the average expression level of all genes in that cluster during the time course (20-min intervals over 1 h) in the strain and condition indicated. Absolute intensity values were normalized for each gene over all 32 conditions examined by subtracting the average expression level for that gene over the all conditions and dividing by the standard deviation for that gene. Thus, expression values (_y_-axis units) are represented as the standard deviations of each time point from the average expression value for each gene over the entire set of experiments. Error bars indicate the standard deviation in expression values of all genes in the cluster at the indicated timepoint.

Abbreviations: Wt + Glu, glucose addition to strain Y2864; Wt + Gal, galactose addition to strain Y2864; RAS2* + Gal, galactose addition to strain Y2866; GPA2* + Gal, galactose addition to strain Y2876; tpk-w + Glu, glucose addition to strain Y2872.

Figure 2

doi: https://doi.org/10.1371/journal.pbio.0020128.g002