Parallel Chemical Genetic and Genome-Wide RNAi Screens Identify Cytokinesis Inhibitors and Targets (original) (raw)
Figure 2
Predicted Functional Annotations of 214 Genes Associated with RNAi Binucleate Phenotypes
Functional groups were assigned using Gene Ontology information presented in FlyBase or the literature (see Table S4). Genes involved in processes associated with cytokinesis are shown in shades of yellow, nucleic acid and protein synthesis and degradation in shades of red, and uncharacterized genes in shades of blue. The uncharacterized genes encode protein sequences that predict recognizable domains (“putative domain”), no recognizable domains (“no recognized domain”), or new gene predictions from the reannotation of the Drosophila genome used as the basis of the dsRNA library (“new annotation”).