Rapid Redistribution of Synaptic PSD-95 in the Neocortex In Vivo (original) (raw)
Figure 5
Larger Spines Retain PSD-95 Longer
(A) Image of two photoactivated spines, a and b, on two branches of the same dendrite. Ga,max and Gb,max are the fluorescence intensities of PSD-95-paGFP* immediately after photoactivation, a measure of PSD size. τ_a,_ and _τ_b are the corresponding retention times.
(B) Comparison of retention times and PSD sizes for pairs of spines. Each line corresponds to a pair of spines, a and b (black, positive slope, n = 64; gray, negative slope, n = 18, 6 animals; orange, example from [A]). Spines with larger PSDs have longer retention times.