When Learning and Remembering Compete: A Functional MRI Study (original) (raw)
Figure 3
fMRI Results
For the purpose of illustration, all activations are shown at p < 0.005.
(A) Interaction between stage (E/R) and outcome (+/-) in PCC, E– = (R–E– and R+E–), E+ = (R–E+ and R+E+), R– = (R–E– and R–E+), R+ = (R+E– and R+E+).
(B) A thre-step analysis indicated encoding suppression in the visual cortex and medial temporal lobe during concurrent retrieval. In step 1, a “localizer” task identified regions related to scene processing. In step 2, we defined encoding success areas within the remaining regions using the contrast R–E+ > R–E–. In step 3, we tested whether the mean encoding success activity of the remaining regions was reduced when successful retrieval happened concurrently.
(C) Greater activity in left mid-VLPFC during concurrent, as compared to separate, successful encoding and retrieval (R+E+ > R+E– and R–E+). Bar graphs indicate the mean of all activated voxels (p < 0.001, uncorrected).