Most “Dark Matter” Transcripts Are Associated With Known Genes (original) (raw)
Figure 7
Examples of identified TUs.
(A) Evidence for the presence of an alternative promoter at the human SLC41A1 gene. Splice junctions connecting to the alternative promoter region are indicated in red. Mapped RNA-Seq data for the UHR paired-end (PE) read sample is shown for reference (black). The PhastCons conservation track scores were based on multiple alignments of 28 vertebrates. (B) Protein-coding TU detected in an intergenic region on chromosome 17, with high similarity to the elongation factor Tu GTP binding domain. The two additional upstream transcribed regions may be part of the same transcript, though no junction sequences were detected. (C) Intergenic TU (red) detected on chromosome 15 based on junctions in the PE brain, PE UHR, and SE testes RNA-Seq samples.