Polymorphic Cis- and Trans-Regulation of Human Gene Expression (original) (raw)
Figure 2
Allelic expression from RNA-Seq confirms prediction by association analysis.
Graphical presentations of two genes that show differential allelic expression. The thick lines represent the higher expressing allelic forms of CHI3L2 and CRYZ (A). Regression of expression phenotypes (expression levels shown on vertical axis) of two genes on nearby SNPs (genotypes shown on horizontal axis) (B). Number of reads (vertical axis) from RNA-Seq for each allelic form (horizontal axis) of the genes; only data for individuals who are heterozygous at the coding SNPs are shown. For each individual, the number of reads for each allele of an SNP is connected by a line. For example, in the panel for rs8535 (CHI3L2), the individual represented by a red line had 268 reads of the A-bearing form of CHI3L2 and 49 reads of the C-bearing form of CHI3L2 (C).