Developmental Changes in the in Vitro Activated Regenerative Activity of Primitive Mammary Epithelial Cells (original) (raw)
Figure 8
Microarray analysis of differentially expressed genes in MRU-enriched fetal and adult basal subsets of mammary cells.
(A) Comparison of transcripts detected in Agilent arrays of extracts of E18.5 fetal (CD31−CD45−Ter119−EpCAM++CD49f+) and adult basal (CD31−CD45−Ter119−BP-1−EpCAM+CD49f+) cells. Expression values of both datasets are shown as log2-normalized values. Shown in pink are the genes (probes) identified as significantly differentially expressed (≥2-fold, _p_≤0.05). (B) Heat map of the top 1% of differentially expressed genes (probes) that were higher in the fetal dataset and the top 1% of differentially expressed genes (probes) that were higher in the adult basal dataset (shown as log2 normalized gene expression values from panel A).