Contact-Inhibited Chemotaxis in De Novo and Sprouting Blood-Vessel Growth (original) (raw)
Figure 12
Evolution of the compactness (C = _A_cluster/_A_hull) of 256-cell clusters on 500×500-pixel lattices (∼1,000 µm×1,000 µm) vs. time for standard Savill-Hogeweg [36] extension-retraction chemotaxis (solid and dashed curves, for T = 50 and T = 200 respectively), and for extension-only chemotaxis (dash-dotted curve, T = 200), with only extending pseudopods responding to the chemoattractant.
Black curves show the mean of 100 simulations. Dotted grey curves mark one standard deviation. Insets: Representative configurations after 1000 (∼8 h) and 5000 MCS (∼40 h). Videos available online.