Number of classes not enriched in GO-terms with high significance.
A Number of classes not significantly enriched below the level after Bonferroni-correction in any of the GO categories biological process, molecular function or cellular compartment. B Number of classes not significantly enriched below the level after Bonferroni correction in at least one the GO categories biological process (BP), molecular function (MF) or cellular compartment (CC). Note the different scales. Clearly, the non-diagonal models consistently produce a lower number of classes which are not enriched in functional annotation. This can be seen as an indication that the non-diagonal models not only represent the network better, but the inferred groups also correspond better to known biology.