Confidence-based Somatic Mutation Evaluation and Prioritization (original) (raw)
Figure 5
Results of mutation validation experiments.
A ROC curve for all 131 mutations with a successful validation (either positive or negative). 1-FDR was used as the probability of a mutation being a true call. B Relative amount of variations found for a given FDR cutoff in a set of 2396 exonic variations which were found in duplicate in two B16 samples (see also Table 1), plotted separately for all variants in the dataset and the 50 validated high confidence mutations. For visual clarity only values of 0 to 0.1 FDR are shown.