Augmenting Microarray Data with Literature-Based Knowledge to Enhance Gene Regulatory Network Inference (original) (raw)
Figure 6
Artificial neural network fitness function.
Each contributory gene's expression in the current time point is magnified by its weight of interaction with the target gene. The sum of these contributions determines the expression level of the target gene at the subsequent time point. t indicates the time point in the microarray dataset, n is the number of genes in the pathway, is the weight of the interaction between gene i and gene j,
is the gene expression value in the microarray set for gene i at time point t.