Single-Cell Co-expression Analysis Reveals Distinct Functional Modules, Co-regulation Mechanisms and Clinical Outcomes (original) (raw)
Fig 5
Interchromosomal interactions are prevalent in single-cell co-expressed genes.
(A) The fraction of co-expressed gene pairs located in the same chromosomes. (B) Map of the co-expressed gene pairs. Each line represent a pair of co-expressed genes. The color of the lines indicates whether they are in the same chromosomes: purple (intrachromosomal), and gray (interchromosomal). (C) The fraction of co-expressed gene pairs located in the same topological domains. (D) The fraction of intrachromosomal and interchromosomal co-expression genes with chromosomal interactions.