Genetic Regulation of Unsaturated Fatty Acid Composition in C. elegans (original) (raw)
Figure 1
Diagram of nhr-80, fat-5, fat-6, and fat-7 Genes and Mutations
(A) nhr-80 is composed of a zinc finger domain (green boxes) and a ligand-binding domain (light blue boxes). nhr-80(tm1011) contains a 446-bp deletion (light grey bar).
(B) fat-5, fat-6, and fat-7 all contain four trans-membrane domains (dark blue boxes) and three histidine boxes (red boxes). fat-5(tm420) consists of a 779-bp deletion (light grey bar). fat-6(tm331) contains a 1,232-bp deletion (light grey bar), and a 428-bp insertion (purple bar). The fat-7 alleles are point mutations with fat-7(wa36), creating a premature stop codon and fat-7(wa37) changing a conserved histidine into a tyrosine.