A Genomic Pathway Approach to a Complex Disease: Axon Guidance and Parkinson Disease (original) (raw)

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Figure 2

Kaplan-Meier Survival Plot for Age at Onset in PD Patients

Data are grouped by categorized risk score from proportional hazards model within our primary whole-genome association dataset [11]. The model clearly differentiates between early-age-at-onset cases and late-age-at-onset cases. Cases generating the long-dashed line were predicted to be at highest risk for early onset of PD, followed by the medium-dashed, short-dashed, and continuous lines, respectively. Since only cases were included, all of the lines end at 0% free of PD.

Figure 2

doi: https://doi.org/10.1371/journal.pgen.0030098.g002