A Genomic Pathway Approach to a Complex Disease: Axon Guidance and Parkinson Disease (original) (raw)
Figure 4
Convergence of Findings for Whole-Genome Association and Gene-Expression Profiling Datasets
Listed are genes that had one or more SNPs included in at least one of the three genetic models that predicted PD susceptibility or survival free of PD or age at onset of PD (n = 45 genes). Expression data are summarized for each of the three nigrostriatal regions (substantia nigra, putamen, and caudate).
Gray, no informative probe sets for the gene and region; white, no difference in expression in cases and controls; red, the gene had increased expression in cases compared to controls; green, the gene had reduced expression in cases compared to controls.