GADD45A Does Not Promote DNA Demethylation (original) (raw)

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Figure 1

GADD45A does not reactivate a methylation-silenced EGFP reporter gene.

HEK293 cells were transiently transfected with an unmethylated (pEGFP-N2) or CpG-methylated (Me-pEGFP-N2) plasmid and the GADD45A expression vector. Fluorescence microscopy indicates that expression of GADD45A does not promote reactivation of EGFP.

Figure 1

doi: https://doi.org/10.1371/journal.pgen.1000013.g001