FtsK-Dependent Dimer Resolution on Multiple Chromosomes in the Pathogen Vibrio cholerae (original) (raw)
Figure 1
FtsK-dependent and FtsK-independent Xer recombination.
A. Chromosome dimer formation and resolution in E. coli. The two homologous chromosomes are depicted by thick and thin lines, to allow for the visualization of crossovers. B. Link between the central region of XerCD-target sites (right) and the recombination pathway adopted at these sites (left). The XerCD-dif recombination complex is viewed from the C-terminal side of the recombinases, to show the C-terminal interactions of XerC and XerD. Strands cleaved by XerC and XerD in E. coli are shown with thick and thin lines, respectively. Positions of strand cleavages by E. coli XerC and XerD are indicated by white and black triangles, respectively. The WebLogo was generated using the alignment of putative dif sites from the larger chromosome of 27 γ-Proteobacteria (Text S1). The XerC-binding site, XerD-binding site and central region of _dif_Ec are indicated below the alignment.