A Systems Approach Reveals Regulatory Circuitry for Arabidopsis Trichome Initiation by the GL3 and GL1 Selectors (original) (raw)
Figure 7
Regulatory motifs controlled by GL1 and GL3.
Circle and squares indicate the nodes of the directed graph representing the regulatory network, and correspond to transcription factors, and enzymes or structure proteins, respectively. Filled lines indicate the edges of the regulatory network, and correspond to direct interactions between transcription factors and the corresponding target genes. The color of the lines originating in the GL3/GL1 first tier regulators indicate whether they correspond to direct targets of GL3 and GL1 (purple), GL3 alone (or perhaps with MYB23, black) or GL1 alone (black). Lines with arrowheads indicate activation by GL3/GL1 whereas lines without arrowheads mean gene regulation is uncertain. The dotted lines derived from the second tier regulators SCL8, GL2, TTG2 and MYC1 correspond to genes from the minimal trichome set most likely downstream of each of the regulators. Boxes shown in the “Trichome genes” tier indicate the corresponding functional classifications. Numbers in bold represent the gene functions classified by FunCat (http://mips.gsf.de/proj/funcatDB/search_main_frame.html). All the genes shown here are described in more detail as part of Table S1.