Nuclear Pore Proteins Nup153 and Megator Define Transcriptionally Active Regions in the Drosophila Genome (original) (raw)
Figure 2
NARs define transcriptionally active regions of the genome.
Genome-track view of 1Mb section on chromosome 2L. NARs are enriched for transcribed genes compared with non-NARs (gene expression track; green shading), and a large proportion of genes are down-regulated upon Nup153-depletion (Nup153 RNAi track; red shading). NARs also align with markers of a transcriptionally active chromatin structure (H4K14Ac, MOF and PolII tracks; grey shading), but exclude markers for inactive chromatin (lamin, H3K27me3; grey shading).