Dual Roles for DNA Polymerase Theta in Alternative End-Joining Repair of Double-Strand Breaks in Drosophila (original) (raw)
Figure 1
Schematic of the mus308 gene.
Exons are represented by boxes. The helicase-like domain (light gray shading) and polymerase domain (dark gray shading) are shown. Locations of the D5, 3294, and 2003 point mutations are indicated with arrows (numbers correspond to amino acid positions in the protein). Not shown is the D2 mutation, which results in severely reduced levels of pol θ.