Chromatin Landscape Dictates HSF Binding to Target DNA Elements (original) (raw)
Figure 3
Bound HSE motifs contain marks of active chromatin prior to HSF binding.
The average factor or histone modification occupancy was assigned in 100 base windows (step size of 50) around HSF-free HSE motifs (red) and HSF-bound HSE motifs (green). HSF-bound motifs are categorized by annotation class: motifs within promoters (magenta), RefGene bodies (blue), and intergenic regions (black). Canonical active chromatin marks are enriched at HSF-bound motifs (purple). H3K27me3 is depleted at HSF-bound motifs (orange).