The Evolution of Host Specialization in the Vertebrate Gut Symbiont Lactobacillus reuteri (original) (raw)
Figure 2
Analysis of genome content by reference microarray.
The dendrogram is derived from UPGMA analysis of binary data generated from 57 strains of Lactobacillus reuteri. Bootstrap scores, using 10,000 repetitions of a UPGMA search, are shown on nodes scoring >50%. Each strain is color coded by host, and affiliation to MLSA lineages of each strain is indicated. MARKFIND was used to identify gene polymorphisms specific to human (MLSA lineage II) and rodent strains (mostly MLSA lineages I and III), which clustered in the dendrogram. The leaves of human (lineage II) and rodent strains, which have been used for comparisons by MARKFIND, are colored blue and red, respectively. The two reference strains, 100-23 and F275, are labeled by a red and a blue circle, respectively. Vertical rectangles to the right depict polymorphisms present in a given strain sorted by the MARKFIND program. Those polymorphisms conserved within all members of a lineage and absent in the other lineage are colored red. Genes that are lineage-specific but non conserved are colored green (polyphyletic) or yellow (monophyletic). Polymorphisms that are not lineage specific are not shown.