Diverse Roles and Interactions of the SWI/SNF Chromatin Remodeling Complex Revealed Using Global Approaches (original) (raw)
Figure 1
SWI/SNF regions co-occur with many diverse genomic elements.
The ChIP-Seq regions and signal tracks displayed encompass a ∼340 kb region on chromosome 6. The coordinates shown are in hg18 and all regions were identified in HeLa cells as detailed in Table S1 and Materials and Methods. Insets A–D are shown both in the context of the 340 kb region and in magnified view. Inset A displays a ∼10 kb region at the edge of a H3K27me3 domain. Inset B displays a ∼10 kb region around the 5′ end of FOXP4. Inset C displays a ∼20 kb region around the 5′ end of MDFI. Inset D shows an example of where lamin A/C and lamin B can both flank and overlap with each other. Annotations above the coordinate axis are for forward-strand genes, and annotations below are for reverse-strand genes. Signal tracks are scaled consistently based on number of reads. The vertical axis for each signal track is the count of the number of overlapping DNA fragments at each nucleotide position and is scaled from 0 to 40 for each track.