Whole-Exome Sequencing and Homozygosity Analysis Implicate Depolarization-Regulated Neuronal Genes in Autism (original) (raw)
Figure 2
A four-dimensional approach to identifying autism candidate genes.
Overview of variant filtration and prioritization of whole exome sequencing data. Results from variant validation and homozygosity analysis were combined with neuronal activity data to identify candidate autism genes from whole exome sequence. 1000G: 1000 Genomes Project, GMCC: genomic mutation consequence calculator, ROHs: runs of homozygosity.