Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import (original) (raw)
Figure 6
LL mutant birth size and fitness are more constrained than those of NLL mutants.
A, The birth size values (y axis) from all 3,842 NLL mutants from S1 Dataset were plotted against their corresponding fitness values (x axis). Because many data points were overlapping, they were binned using the hexbin function of the R software package. The displayed colors represent the number of strains within each bin, as indicated by the color key to the right. B, The birth size values (y axis) from all 137 LL mutants from S1 Dataset were plotted against their corresponding fitness values (x axis), as in A. The number of strains in each bin (counts) are shown on the right.