Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import (original) (raw)
Figure 7
G1 phase cell cycle parameters of LL and NLL strains.
A, The birth size values (y axis) of the 14 LL and 13 NLL strains shown in S4 Table. The filled black squares correspond to the values of the wild type control. The data from S4 Table were used to generate the graphs shown. B, The specific rate of cell size increase (k, shown on the y axis) for the LL and NLL strains shown in S4 Table was calculated from synchronous, elutriated cultures (see Materials and Methods). C, The critical size (y axis) of the LL and NLL strains shown in S4 Table was calculated from the same experiments shown in B. D, LL mutants have efficient cell size control mechanisms. On the x axis is the logarithm of the normalized birth size values of the LL mutants shown in S4 Table, plotted against their relative growth in size during the G1 phase of each strain (_k_TG1, y axis). The dashed line is a linear fit obtained with the regression function of Microsoft Excel. The filled square is the wild type strain.