Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import (original) (raw)

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Figure 8

Stabilization of Tat2p increases birth size and suppresses replicative lifespan extension in hxk2Δ and rpl20bΔ cells.

A and B, The cell size of the indicated haploid cell populations cultured in YPD (2% Dextrose) medium was measured using a channelyzer. Cell numbers are plotted on the y axis and the x axis indicates size (in fL). C and D, Experiment-matched survival curves of the same strains shown in A and B. Mean lifespans are shown in parentheses, along with the number of cells assayed.

Figure 8

doi: https://doi.org/10.1371/journal.pgen.1004860.g008