Allelic Variation of Cytochrome P450s Drives Resistance to Bednet Insecticides in a Major Malaria Vector (original) (raw)
Fig 1
Schematic representation of haplotypes of An. funestus CYP6P9a and CYP6P9b from resistant populations and the susceptible strain FANG, across Africa.
(A) and (B) shows maximum likelihood tree of CYP6P9a and CYP6P9b cDNA sequences which forms clades specific to each phenotype. The small trees on the upper left of the maximum likelihood trees indicate the Nst genetic distances; (C) and (D) shows the polymorphic positions for both CYP6P9a and CYP6P9b amino acid sequences, respectively. A number is given to each haplotype preceded by country of origin (BEN, UGAN, MAL, MOZ, ZMB or FANG, for Benin, Uganda, Malawi, Mozambique, Zambia and FANG strains, respectively). The column Nb stands for the number of individual mosquitoes sharing a haplotype.