Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose (original) (raw)
Fig 8
RNA sequencing data of M. tuberculosis indicates that only the iniBAC operon is regulated through IniR.
(A) The plots contain gene expression profiles in log2 fold change reads per kilobase million (RPKM) of Δ_iniR_ Mtb + INH compared to the control strain, i.e. M. tuberculosis H37Rv WT + INH. (B) Plotted gene expression profile in log2 fold change RPKM of Δ_iniR_ Mtb + EMB compared to H37Rv WT + EMB. The iniBAC genes are indicated with yellow arrows. The experiment was performed with a biological triplicate.