Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes (original) (raw)
Fig 2
Phylogenetic relationships of virus-like contigs from the dog whelk.
Mid-point rooted maximum likelihood phylogenetic trees for each of the virus-like contigs associated with viRNAs in the dog whelk (Nucella lapillus). New virus-like contigs described here are marked in red, sequences marked ‘TSA’ are derived from public transcriptome assemblies of the species named, and the scale is given in amino acid substitutions per site. Panels are: (A) rhabdoviruses related to lyssaviruses, inferred using the protein sequence of the nucleoprotein (the only open reading frame available from this contig, which is likely an EVE); (B) orthomyxoviruses related to influenza and thogoto viruses, inferred using the protein sequence of PB1; (C) rhabdoviruses and chuviruses, inferred from the RNA polymerase. Support values and accession identifiers are presented in S2 Fig and S3 Data, and alignments in S2 Data. Given the high level of divergence, alignments and inferred trees should be treated as tentative.