Acute-Phase Serum Amyloid A: An Inflammatory Adipokine and Potential Link between Obesity and Its Metabolic Complications (original) (raw)

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Figure 5

Rosiglitazone Reduces Serum A-SAA Levels and Adipose A-SAA Production in Humans

Serum A-SAA ( n = 8) (top) and adipose secretion of A-SAA ex vivo ( n = 7) (bottom) were measured in nondiabetic participants before and after 3 mo of rosiglitazone treatment. The data are plotted with lines connecting the A-SAA levels of each individual. Serum A-SAA and adipose secretion of A-SAA (one symbol for same person of both studies) were significantly decreased by rosiglitazone ( p = 0.033 and p = 0.034, respectively; paired _t_-test after log-transformation).

Figure 5

doi: https://doi.org/10.1371/journal.pmed.0030287.g005