Modelling the Impact of Artemisinin Combination Therapy and Long-Acting Treatments on Malaria Transmission Intensity (original) (raw)
Figure 2
Example Model Run over Time for One Age and Exposure Group in One Survey Setting
Initially this shows introduction of infection and baseline endemic equilibrium in the absence of treatment. Nonartemisinins with treatment failure are introduced first and the model is allowed to reach a second equilibrium, matching the prevalence of slide-positive malaria, clinical malaria and self-reported treatment in the Tanzania survey data. ACT or another antimalarial regimen are then introduced, and our main outcomes of interest are the reductions in prevalence and rate of clinical episodes between the second and third equilibriums.