Analysis of Germline GLI1 Variation Implicates Hedgehog Signalling in the Regulation of Intestinal Inflammatory Pathways (original) (raw)
Figure 1
Meta-Analysis of Nonsynonymous GLI1 SNP rs2228226 (tSNP4) in Scotland, Cambridge, and Sweden Using Mantel-Haenszel Method (n = 5,352 Individuals)
(A) IBD versus HCs.
(B) UC versus HCs. There was no evidence of heterogeneity in the contribution of rs2228226 between the three cohorts (p = 0.825). 95% CIs for individual populations are represented by horizontal lines and population sizes by square boxes. The diamond represents the pooled OR (fixed effect model) with 95% CIs delineated by the diamond's width. Note the different range of the _x_-axis for (A) and (B).