Reducing Plasmodium falciparum Malaria Transmission in Africa: A Model-Based Evaluation of Intervention Strategies (original) (raw)
Figure 5
The effect of non-random distribution of interventions.
(A and B) Parasite prevalence after 15 years of an intervention program as a function of the target coverage of (A) LLIN distribution and (B) MSAT for Kinkole, DRC. Blue: if the intervention is distributed randomly; green: if the intervention is preferentially distributed to the youngest children; red: if the intervention is preferentially distributed to those who are bitten most frequently (excluding age dependency in biting rates). (C and D) Parasite prevalence after 15 years of a single intervention program as a function of the frequency of the intervention and whether successive rounds are given randomly (green) or to the same people (purple) for Kinkole, DRC. (C) IRS; (D) MSAT. (E and F) Parasite prevalence in all individuals (red), in 2- to 10-year-olds (blue) and EIR (green) after 15 years of a combined intervention program as a function of the correlation in receipt of the two interventions for KND, Ghana. A correlation of 0 represents random distribution at each round, 1 represents those receiving one intervention also receive the other and −1 represents those receiving one intervention do not receive the other. (E) IRS and LLIN; (F) IRS and MSAT. For (E) and (F) there is 50% coverage per round for IRS and MSAT and the baseline scenario for LLINs.