Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni (original) (raw)
Figure 1
In vitro efficacy of 10−5 M PZQ in killing S. mansoni miracidia after 20 minutes of exposure in 96 well plates.
Miracidia were hatched from fecal samples collected from human patients from the Kisumu area in Kenya, and the assay run in triplicate. The percentage of miracidia dead at the end of the 20 min observation period is graphed. Error bars correspond to standard error of the mean. Numbers above bars correspond to number of PZQ treatments. Data for parasites obtained from sand harvesters are indicated by squares and circles for car washers.