Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni (original) (raw)
Figure 2
Average number of S. mansoni adult worms perfused from mice, following treatment with 1000 mg/kg of PZQ in Cremaphor 2% EL.
Treatment was administered at 7.5 weeks p.i., and mice perfused 2 weeks after treatment. Efficacy of treatment was calculated as described in text. The p values for the comparison between mean # of worms recovered from control versus treated groups were as follows: KCW, p = 0.072; the sample size for KAS was too small to assess statistical significance; KNY, p<0.0001; PR1, p<0.0001; NMRI, p<0.0001. Error bars correspond to standard error of the mean.